Mouse skin epithelial cells are primary cells derived from the outer layer of mouse skin, primarily the epidermis. These cells play a critical role in maintaining skin barrier function, wound healing, and protecting against pathogens. They serve as a widely used model in dermatological and toxicological research due to their biological similarity to human skin cells.
Epithelial cells in the skin form tightly connected layers that protect underlying tissues and regulate the exchange of substances. Mouse skin epithelial cells are particularly valuable in studying skin regeneration, inflammation, and the effects of various topical treatments or environmental exposures.
Researchers often use these cells to investigate molecular pathways involved in skin disorders such as psoriasis, dermatitis, and skin cancer. When cultured in vitro, mouse skin epithelial cells help simulate skin conditions and evaluate the efficacy and safety of new skincare or pharmaceutical agents, making them essential tools in preclinical dermatology studies.
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